The influence of supplementation of probiotic cheese and flax-seed on immune response of piglets
2012
Firmentová, S., University of Veterinary Medicine and Pharmacy in Košice | Mudroňová, D. | Nemcová, R. | Gancarčíková, S.
The aim of this study was to observe the influence of the supplementation of probiotic lactobacilli in the form of cheese and/or flaxseed as a source of omega-3 polyunsaturated fatty acids (PUF A), on the clinical state and cellular immune response of piglets at the time of weaning. The experiments were carried out on 72 healthy piglets divided to 4 equal groups: control (C), lactobacilli (L), fatty acids (FA) and a combination of lactobacilli and fatty acids (LFA). Six animals from each group were used for an immunological analysis (the day of weaning and days 7 and 21 post-weaning). In all experimental piglets we observed a shorter durations of diarrhoea and lower faecal scores compared with the controls. The local intestinal immune response was affected significantly by day 7 post-weaning. Significantly higher proportion of B-lymphocytes (CD 21) was observed in the LFA group in comparison with all other groups. The total immune response was affected significantly only on day 21 post-weaning. We observed an increase in the subpopulations of CD 3 lymphocytes and parallel decreases in the CD 4 subpopulations in the experimental groups compared with the control. A decrease in phagocytic activity in the FA group was compensated in the LFA group by the supplementation of probiotic lactobacilli. An increase in the metabolic flare up of phagocytes in the FA group was most likely related to the high content of omega-3 PUF A.
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