Genetic polymorphism of serum albumin in the Carpathian breed in econogenic interrelation with other goat breeds
2011
Hrinca, G.
This paper has proposed to reveal the albumin polymorphism in goats belonging to the Carpathian breed. Identification of albumin phenotypes was performed from blood serum of animals by starch gel electrophoresis method. Depending on the migration speed of albumin fractions, three phenotypes were found: homotype AlbFF (with fast electrophoretic migration), homotype AlbSS (with slow electrophoretic migration) and heterotype AlbFS (with intermediate electrophoretic migration). Emergence of albumin phenotypes is due to the two co-dominant autosomal alleles, AlbF and AlbS, whose distribution is unequal within the population, the allele AlbS being very common (83.66%) compared to allele AlbF (16,34%). Unequal spread of these alleles causes a differentiated distribution of albumin genotypes: homozygotes AlbS AlbS are the most common (70.24%), heterozygotes AlbF AlbS are enough well represented (26.83%), and homozygotes AlbF AlbF register a very low frequency (2.93%). As a result, the summed homozygosity (AlbF AlbF + AlbS AlbS is three times more frequent (73.17%) than heterozygosity AlbF AlbS (26.83%). The Carpathian breed is in Hardy-Weinberg genetic equilibrium at the locus Alb, both at the level of individual albumin genotypes, as well as regarding the general status of albumin zigosity. From the econogenic point of view, the Carpathian breed is similar to several breeds of goats of the Central and Eastern Europe.
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