Targeting inflammation for prevention and treatment of cancer by tocotrienols : food for thought
2007
Aggarwal, Bharat B. | Kwang, Seok Ahn
Tocotrienols are the active components of wide variety of plants including palm, rice bran, coconut, oats, and wheat. Unlike the tocopherols, the tocotrienols, also members of the vitamin E family, have an unsaturated isoprenoid side chain. In contrast to extensivestudies on tocopherol, very little is known about tocotrienols. We present evidence that tocotrienols may have a potential in treatment of cancer, cardiovascular diseases, bone loss, arthritis and other proinflammatory diseases through the suppression of NF-KB pathway.
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