FAO World Animal Review | A review of the prospects for vaccination in African trypanosomiasis. Part I
1979
Murray, M. | Barry, J.D. | Morrison, W.I. | Williams, R.O. | Hirumi, H. | Rovis, L.A.
This review of the prospects for developing an immunization procedure against trypanosomiasis explores a number of promising avenues of research. Part I covers variable antigen types (VATs); metacyclic antigens; in vivo and in vitro attenuation; and molecular and genetic engineering. Part II, to be included in the next issue of this journal, will cover immunogenicity of subcellular fractions; immunological intervention against the tsetse fly; induction of increased resistance by immunostimulants; trypanotolerance; and infection and treatment. This will be followed by a brief statement of the conclusions reached.
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