Effects of dietary acetaminophen and vitamin C supplement on serum cortisol and tumor necrosis factor-alpha concentrations in pigs vaccinated with foot-and-mouth disease vaccine
2017
Cha, C.N., Gyeongsang National University, Jinju, Republic of Korea | Lee, B.J., Chungbuk National University, Cheongju, Republic of Korea | Park, E.K., Kosin University, Busan, Republic of Korea | Yoo, C.Y., Gyeongnam Provincial Namhae College, Namhae, Republic of Korea | Kim, S., Gyeongsang National University, Jinju, Republic of Korea | Lee, H.J., Gyeongsang National University, Jinju, Republic of Korea
This study evaluated the effect of a combination of acetaminophen and vitamin C (CAV) on reducing serum cortisol and tumor necrosis factor-alpha (TNF-alpha) concentrations in piglets vaccinated with foot-and-mouth disease (FMD) vaccine. Piglets were vaccinated with FMD vaccine and treated with CAV at concentrations of 0.0, 0.5, 1.0, and 2.0 kg/ton feed (P-CON, AD-1, AD-2, and AD-3, groups, respectively) for 5 days post-vaccination. Cortisol and TNF-alpha levels at 5 days post-treatment in the AD-1-3 groups were significantly lower than that in the P-CON group (p less than 0.05). There were no significant differences between AD-2 and AD-3 groups and non-vaccinated, non-CAV-treated piglets.
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