Bioactive Component Analysis, Antioxidant Activity, and Cytotoxicity on Cancer Cells on Rubus crataegifolius Clones by Region
2016
Choi, E.Y., Daegu Haany University, Gyungbuk, Republic of Korea | Kim, E.H., Daegu Haany University, Gyungbuk, Republic of Korea | Lee, J.B., Daegu Haany University, Gyungbuk, Republic of Korea | Kim, H.S., National Institute of Forest Science, Suwon, Republic of Korea | Kim, M.S., National Institute of Forest Science, Suwon, Republic of Korea | Lee, S.G., National Institute of Forest Science, Suwon, Republic of Korea | Kim, S.H., National Institute of Forest Science, Suwon, Republic of Korea | Lee, U., National Institute of Forest Science, Suwon, Republic of Korea | Kim, D.K., Korea Dyeing and Finishing Technology Institute Advanced Processing Development Center, Daegu, Republic of Korea | Lee, J.T., Daegu Haany University, Gyungbuk, Republic of Korea
This study was carried out to analyze the nutritional composition, bioactive components, antioxidant activity, and cytotoxic assay of cancer cells on Rubus crataegifolius (RC) : R. crataegifolius from Jangseong (RC-J), R. crataegifolius from Hwaseong (RC-H), R. crataegifolius from Ulsan (RC-U), R. crataegifolius from Sunchang (RC-S), and R. crataegifolius from Pohang (RC-P). The peroximate composition had the largest amount of carbohydrate content among all kinds of RC. As far as the mineral contents of RC, Calcium comprised the highest amount (996.6 μg/g ± 0.8%) and Natrium the lowest (6.2 μg/g ± 1.0%). A total of 26 kinds of free amino acids and 18 kinds of component amino acids were analyzed in RC. The results of electron donating were high scavenging effects of 80% in water extract (RC-UW) and 82.6% in ethanol extract (RC-UE) in 500 μg/ml concentration from RC-U. Also, the cytotoxic effects of cancer cells B16F10 (RC-UW and RC-PE), H1299 (RC-SW and RC-PE), and MCF-7 (RC-JW and RC-SE) appeared in RC. Therefore, we confirmed that new varieties may possibly be developed with functional materials.
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