Clinical application of quantitative computed tomography in osteogenesis imperfecta-suspected cat
2017
Won, S., Irion Animal Hospital, Seoul, Republic of Korea | Chung, W., Ray Veterinary Medical Center, Seoul, Republic of Korea | Yoon, J., Seoul National University, Seoul, Republic of Korea
One-year-old male Persian cat presented with multiple fractures and no known traumatic history. Marked decrease of bone radiopacity and thin cortices of all long bones were identified on radiography. Tentative diagnosis was osteogenesis imperfecta, a congenital disorder characterized by fragile bone. To determine bone mineral density (BMD), quantitative computed tomography (QCT) was performed. The QCT results revealed a mean trabecular BMD of vertebral bodies of 149.9 ± 86.5 mg/cm3. After bisphosphonate therapy, BMD of the same site increased significantly (218.5 ± 117.1 mg/cm³,p less than 0.05). QCT was a useful diagnostic tool to diagnose osteopenia and quantify response to medical treatment.
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