Cytogenetic monitoring in a Serbian population exposed to pesticides: use of micronuclei
2015
Jovičić , Dubravka (Singidunum University, Belgrade (Serbia). Faculty of Applied Ecology) | Radivojević, Ljiljana (Institute of Pesticides and Environmental Protection, Belgrade (Serbia)) | Janjić, Vaskrsija (Institute of Pesticides and the Environment, Belgrade (Serbia))
Aim of this study was to assess the damage to the genetic material, detected with the micronucleus test in workers occupationally exposed to pesticides. The research included 119 subjects divided into three groups: the control group, there were 39 subjects, in the group exposed to pesticides (producers) were 40 subjects and 40 subjects - applicants in the field, were analyzed in this paper. Mann-Whitney U test showed a statistically significant difference between the mean values of the parameters of all variables compared to the control group. Significant differences between males in production and application for parameters MN4, then among nonsmokers in the production and application for parameters MN2, MN3, MN4and NB, as well as in the whole population observed between control and applicants for parameter MN2, and between producers and applicants for parameter MN3. A statistically significant difference in relation to the cytogenetic parameters studied was registered between respondents who work in the production of pesticides and of those who work in the field. The results suggest that workers who are working in the field do not use adequate personal protective equipment. The continuous biological monitoring of workers exposed to pesticides is required.
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