Relative contribution of oxalic acid, phytate and tannic acid on the bioavailability of calcium from various calcium salts - an in vitro study
2017
Pius, A. | Amalraj, A.
Calcium is important for bone and teeth health. Due to its vital role in human health, people are aware about calcium intake through diet and from other supplements. But, it is not only the amount of intake but actual dose absorbed by the body plays important role. The objective of this study was to determine and compare the amount of bioavailable calcium from various calcium salts like calcium carbonate, calcium citrate, calcium formate, calcium gluconate andcalcium lactate by in vitro method using equilibrium dialysis after simulating gastric digestion. Selected calcium salt solutions were used as the source of calcium, to which a series of inhibitors like oxalic acid, phytate and tannic acid of calcium absorption were added separately at various concentrations, and the extent of bioavailable calcium was determined. Among the salts studied, calcium citrate registered higher percentage of bioavailable calcium and amongthe inhibitors, oxalic acid decreased maximum bioavailable calcium in all selected calcium salts.
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