Immunoassays for determination of antigens and allergens in latex products
1994
Cardosa, M. J. | Samuel-Verghese, S. | Sharifah Hamid | Yeang, H. Y.
The quality control of latex products used in the medical setting has to take into account the presence of allergens which induce a Type I hyper sensitivity response. Assays to measure the total protein eluted from these products + does not address the problem of allergenicity of the proteins extracted. This paper introduces to rubber manufacturers the concept of enzyme irrmunoassay and describes various immunoassay formats by which antigens can be detected. The paper further + describes a number of examples which show that gloves produced by different manufacturers contain different amounts of antigens and monoclonal antibodies are used to show that different antigens are found in different gloves.
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