Genetic analysis of chromosomal region 97D2-9 of Drosophila melanogaster
1993
Knibb, W.R. (Adelaide Univ. (Australia). Dept. of Biochemistry) | Tearle, R.G. | Elizur, A. | Saint, R.
The rough homeobox gene of Drosophila melanogaster is required for the correct patterning of the developing eye. The locus maps to cytological location 97D2-5, a region which has not been extensively characterised. As part of the genetic and molecular characterization of rough an EMS mutagenesis was carried out to generate mutants that map to the surrounding region, 97D2-9 which is, deleted in DS(3R)ro-XB3. One visible and 13 lethal mutations were generated which, together with the previously described Toll and ms(3)K10 loci, and other unpublished lethals, define nine complementation groups - four lethal, three semi-lethal, one visible and one male-sterile. In addition to rough, one other locus within this region, 1(3)97De, was shown to be required for formation of the normal pattern of photoreceptor cells in the compound eye.
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