25-hydroxyvitamin D circulates in different fractions of calf plasma if the parent compound is vitamin D₂ or vitamin D₃, respectively
2016
Hymøller, Lone | Jensen, Søren K
Vitamin D has become one of the most discussed nutrients in human nutrition, which has led to an increased interest in milk as a vitamin D source. Problems related to fortifying milk with synthetic vitamin D can be avoided by securing a high content of natural vitamin D in the milk by supplying dairy cows with sufficient vitamin D. However, choosing the most efficient route and form of supplementation requires insight into how different vitamin D metabolites are transported in the body of cattle. There are two forms of vitamin D: vitamin D₂ (D₂) and vitamin D₃ (D₃). Vitamin D₂ originates from fungi on roughage. Vitamin D₃ originates either from endogenous synthesis in the skin or from feed supplements. Vitamin D₂ is chemically different from, and less physiologically active than, D₃. Endogenous and dietary D₃ is chemically similar but dietary D₃ is toxic, whereas endogenous D₃ appears well regulated in the body.
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