Three new norlignans from Glechoma longituba
2013
Zhu, Qiu-Fang | Wang, Yong-Yi | Jiang, Wei | Qu, Hai-Bin
Three new norlignans, glechomols A–C (1–3, respectively), together with a known compound, 4-ethylcatechol (4), were isolated from the ethyl acetate extract of Glechoma longituba (NaKai) Kupr. Their structures were elucidated by the detailed analysis of 1D and 2D NMR and HR-MS data. Glechomols A–C were the first norlignans reported from genus Glechoma, and compound 4 was also isolated from genus Glechoma for the first time. Intracellular antioxidant assays showed that compounds 1–4 displayed significant protective effects on H₂O₂-induced cardiac cell injury.
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