5' Avian leukosis virus sequences and osteopetrotic potential

Robinson, H.L.; Foster, R.G.; Blais, B.P.; Reinsch, S.S.; Newstein, M.; Shank, P.R.

5' Avian leukosis virus sequences and osteopetrotic potential

1992

Recombinants of Rous-associated virus-0 and Br21 have been used to localize 5' viral sequences that affect the osteopetrotic potential of avian leukosis viruses. Rous-associated virus-0 is a benign subgroup E virus of endogenous origin that does not cause osteopetrosis. Br21 is a constructed subgroup E virus with high osteopetrotic potential. 5' sequences that affected osteopetrotic potential resided in an 834-bp region near the 5' LTR. Sequence analysis of this region revealed differences between Br21 and RAV-0 in the mRNA leader and codons for MA.

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AGROVOC Keywords

animals avian leukosis virus avian oncovirus chickens chicks cloning codon disease severity dna genetic recombination genetics microbiology pathogenicity plasmids recombination repetitive sequences rna viremia

Bibliographic information

Published in

Virology

Volume 190 Issue 2 Pagination 866 - 871 ISSN 0042-6822

Publisher

John Wiley & Sons, Ltd

Other Subjects

Messenger; Molecular; Incidence; Gender differences; Comparisons; Nucleic acid; Viral; Base sequence; Osteopetrosis; Genetic; Nucleotide sequences; Restriction mapping; Genome; Avian osteopetrosis; Molecular sequence data

Language

English

Type

Journal Article; Text

In AGRIS since: 2024-02-27

Format: MODS

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5' Avian leukosis virus sequences and osteopetrotic potential

1992

AGROVOC Keywords

Bibliographic information