Seronegative Myasthenia Gravis with Concomitant SARS-CoV-2 Infection in a Dog
2022
Musteata, Mihai | Borcea, Denis-Gabriel | Despa, Andreea | Ștefănescu, Raluca | Ivănescu, Larisa | Hrițcu, Luminița Diana | Baisan, Radu Andrei | Lăcătuș, Radu | Solcan, Gheorghe
Myasthenia gravis (MG) is a disorder of neuromuscular transmission affecting the neuromuscular junction. The majority of cases involve an autoimmune attack against AChR, but a limited number of patients are seronegative for AChR antibodies. Viral infection is incriminated as a trigger for MG occurrence, and in a limited number of reports, infection with SARS-CoV-2 was found to be associated with MG expression in humans. In this report, we describe case of seronegative generalized MG in a 2-year-old crossbred female dog associated with SARS-CoV-2 infection due to close exposure to an infected owner.
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