Comparison of preoperative to postoperative blood glucose in puppies undergoing elective surgical neutering
2022
Fudge, J.M. | Lee, I. | Page, B. | Jeffery, U.
The objective of this study was to determine if overnight fasting is associated with hypoglycemia in puppies undergoing elective surgical neutering. One hundred seventy-one apparently healthy puppies between the age of 2 and 6 months presented for elective surgical neutering. Owners were instructed to withhold food from puppies after midnight the night before surgery; water was to be freely available. Blood samples were collected pre- and postoperatively to determine blood glucose, packed cell volume (PCV), and serum total protein (TP). Pre- and postoperative data were compared with a paired Wilcoxon test (paired samples). Hypoglycemia was defined as glucose < 4.2 mmol/L (76 mg/dL) for pediatric puppies ≤ 16 weeks of age (n = 116), and < 3.6 mmol/L (65 mg/dL) for juvenile puppies > 16 weeks of age (n = 55). Blood glucose significantly increased after surgery from median 8.8 mmol/L (interquartile range [IQR], 1.7 mmol/L; range, 4.9–12.3 mmol/L) to a median 9.7 mmol/L (IQR, 1.8 mmol/L; range, 5.4–14.7 mmol/L; P < 0.0001). Preoperative median PCV was 35% (IQR, 6.5%; range, 26–53%) and TP was 58 g/L (IQR, 6 g/L; range, 44–82 g/L). Preoperative values were significantly higher than postoperative values for PCV (median, 31%; IQR, 4%; range, 24–43%) and TP (median, 55 g/L; IQR, 7 g/L; range, 40–76 g/L; P < 0.0001). No puppy developed hypoglycemia and no adverse events were observed or reported. Overnight fasting did not result in pre- or postoperative hypoglycemia in studied puppies undergoing elective neutering.
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