Kinetic resolution of 2-substituted-2,3-dihydrofurans by a palladium-catalyzed asymmetric Heck reaction
2015
Li, Hao | Wan, Shi-Li | Ding, Chang-Hua | Xu, Bin | Hou, Xue-Long
The kinetic resolution of 2-substituted-dihydrofurans via a palladium-catalyzed asymmetric Heck reaction was realized, providing optically active 2-substituted-dihydrofurans and trans-2,5-disubstituted-dihydrofurans in high yield and good enantioselectivities with an S factor up to 70.
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