Cisplatin-encapsulated organic nanotubes by endo-complexation in the hollow cylinder
2012
Ding, Wuxiao | Wada, Momoyo | Minamikawa, Hiroyuki | Kameta, Naohiro | Masuda, Mitsutoshi | Shimizu, Toshimi
A bipolar glycolipid self-assembles into organic nanotubes upon its chelation with an anticancer drug cis-dichlorodiamineplatinum(ii) (CDDP). The facile synthesis of glycolipid, chelation-assisted formation of the nanotubes, and efficient loading and prolonged release of CDDP demonstrate a new approach to high-axial supramolecular drug nanocarriers.
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