The JAK-STAT pathway in Drosophila

Hou, X.S.; Perrimon, N.

The JAK-STAT pathway in Drosophila

1997

Hou, X.S. | Perrimon, N.

Recent studies in Drosophila have identified a single JAK and a single STAT protein. Genetic and biochemical analyses reveal that these two proteins operate in the same signal transduction pathway. Phenotypic analyses of JAK and STAT mutants implicate this pathway in a number of developmental decisions, in particular the regulation of pair-rule genes and fly hematopoiesis.

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AGROVOC Keywords

animals cell division drosophila drosophila melanogaster embryogenesis embryology gene expression regulation genetics larva literature reviews metabolism mutants mutation neoplasms transcription factors transcription factors

Bibliographic information

Published in

Trends in genetics

Volume 13 Issue 3 Pagination 105 - 110 ISSN 0168-9525

Publisher

Systematic and Applied Acarology Society

Other Subjects

Dna-binding proteins; Drosophila proteins; Transcription (genetics); Protein-tyrosine kinases; Stat5 transcription factor; Genetic techniques and protocols; Genetic regulation; Female; Trans-activators; Milk proteins; Signal transduction; Janus kinases; Developmental; Stat transcription factors; Embryo; Nonmammalian

Language

English

Type

Journal Article; Text

In AGRIS since: 2024-02-28

Format: MODS

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The JAK-STAT pathway in Drosophila

1997

AGROVOC Keywords

Bibliographic information