Ribosome Assembly in Trypanosomatids: A Novel Therapeutic Target
2017
Kamina, Anyango D. | Williams, Noreen
In Liu et al., the authors present a 2.5-Å structure of the Trypanosoma cruzi 60S ribosomal subunit and propose a model for the stepwise assembly of the large-subunit ribosomal RNA (rRNA). Based on this study, we discuss how the unique features of trypanosomatid ribosome assembly offer potential drug targets.
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