Effects of hyperthermia on blood constituents in the domestic rabbit (Lepus cuniculus)
1994
1. Effects of exposing rabbits to temperatures 37-50 degrees C on body-core temperature and some blood constituents were investigated. 2. Heat stroke death occurred at or above a critical core-temperature of 43.0 degrees C. 3. Plasma osmolality and levels of glucose, urea and lactate were significantly elevated in hyperthermia. 4. Widespread tissue damage was indicated by increases in plasma activities of glutamate oxaloacetate transaminase (GOT), glutamate pyruvate transaminase (GPT) and creatinine phosphokinase (CPK). 5. The most sensitive indicators of impending heat stroke in heat stressed rabbits were plasma levels of urea, lactate and CPK.
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