Effects of thyroid hormones on serum and cutaneous fatty acid concentrations in dogs

Campbell, K.L.; Davis, C.A.

Effects of thyroid hormones on serum and cutaneous fatty acid concentrations in dogs

1990

Campbell, K.L. | Davis, C.A.

The effects of thyroid hormones on the serum and cutaneous fatty acid concentration profiles of dogs were evaluated. Thyroidectomized dogs had significant (P < 0.05) increases in serum oleic acid and linoleic acid concentrations, and decreases in concentration of dihomo-gamma-linolenic acid, arachidonic acid, and other elongation products of fatty acid metabolism. These changes were reversed in response to thyroid hormone replacement. Similar changes were found in cutaneous fatty acid concentration profiles. Thus, in dogs, thyroid hormones may be involved in the regulation of fatty acid delta-6-desaturase activity.

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AGROVOC Keywords

animals blood blood serum cholesterol dogs dogs enzyme activity enzymes fatty acids fatty acids hormonal regulation lipid metabolism metabolism pharmacology radioimmunoassay skin thyroid hormones thyroxine triglycerides

Bibliographic information

Published in

American journal of veterinary research

Volume 51 Issue 5 Pagination 752 - 756 ISSN 0002-9645

Other Subjects

Time factors; Administration & dosage; Veterinary; Thyroidectomy; Random allocation; Stearoyl-coa desaturase; Thyroid function tests; Delta-6-desaturase; Thyroidectomy; Male

Language

English

Note

2019-12-04

Type

Journal Article; Text

In AGRIS since: 2024-02-28

Format: MODS

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