Bone mineral content and serum 25-hydroxyvitamin D concentrations in breast-fed infants with and without supplemental vitamin D: One-year follow-up
1982
Greer, Frank R. | Searcy, John E. | Levin, Ronald S. | Steichen, Jean J. | Steichen-Asche, Paule S. | Tsang, Reginald C.
A 1 year follow-up report on 18 totally breastfed infants was done to detemine if vitamin D supplementation was essential to alleviate decreased in bone mineral content (BMC), and serum 25 hydroxyvitamin D (25-OH vitamin D). The infants were placed into 2 groups of 9 each (1 group received a placebo; 1 group 400 IU of vitamin D/day). Twelve formula fed infants served as the control group. At 12 and 26 weeks infants receiving the placebo had significantly less BMC than the supplemented breast-fed or formula fed infants. The conclusions drawn were that low serum 25-OH vitamin D concentrations and early decreases in BMC did occur in breastfed infants not receiving supplementation which may be necessary if optimal growth in length is desired. (kbc)
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