Daintain/AIF-1 Reinforces the Resistance of Breast Cancer Cells to Cisplatin
2012
JIA, Shaohui | CHAIBOU, Moctar Ali | CHEN, Zhengwang
Our previous studies revealed that daintain/AIF-1 promoted the proliferation and migration of breast cancer cells. In the present study, we investigated the effect of daintain/AIF-1 on the cisplatin resistance of breast cancer cells. The results indicated that daintain/AIF-1 reinforced the resistance of breast cancer cells to cisplatin by inhibition of cell apoptosis and reduction of intracellular cisplatin accumulation.
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