7-Phenyl-1,2,4-triazolo[1,5-a]pyrimidines and related heterocycles: a new family of bleaching herbicides
1992
Selby, T.P. | Andrea, T.A. | Denes, L.R. | Finkelstein, B.L. | Fuesler, T.P. | Smith, B.K.
Substituted 7-phenyl-1,2,4-triazolo[1,5-a]pyrimidines and related heterocycles represent a new family of highly active herbicides which have demonstrated activity at rates as low as 31 g/ha. This class of compounds has shown broad-spectrum weed control with selectivity to key crops such as cereals, cotton, and rice. The mode-of-action was shown to be inhibition of phytoene desaturase, an enzyme involved in carotenoid biosynthesis. A summary of the discovery, synthesis, structure/activity and mode-of-action of this class of herbicides is reported.
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