Effect of a Lipid Complex from the Marine Red Alga Ahnfeltia tobuchiensis on the Metabolic Responses of the Liver under Conditions of Experimental Toxic Hepatitis
2021
Sprygin, V. G. | Kushnerova, N. F. | Fomenko, S. E.
The effect of a lipid complex isolated from a water–ethanol extract of the thallus of the red alga Ahnfeltia tobuchiensis (ahnfeltia lipid complex (ALC)) on the biochemical parameters of the blood and liver of mice intoxicated by carbon tetrachloride has been studied. It is shown that the administration of ALС had a significant antioxidant and hepatoprotective effect; it was more efficient than the Essentiale® reference hepatoprotector in terms of the ability to restore the animal weight, specific liver weight, AlAT activity, and lipid metabolism and to reduce lipid peroxidation. The hepatoprotective effect of the ALС is determined by the action of its constituent phospholipids and glycolipids of marine origin, characterized by a high content of polyunsaturated fatty acids of group n-3.
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