Selenium bioavailability: the effect of guar gum supplementation on selenium utilization by human subjects
1989
Choe, M. | Kies, C.
The objective of the present study was to determine the effect of guar gum supplementation on selenium utilization in humans. Fifteen subjects were fed a laboratory-controlled diet with and without supplements of selenium or selenium plus guar gum. Selenium supplementation resulted in increased selenium excretion in urine and feces. Supplementation with guar gum tended to increase fecal selenium excretion and to decrease selenium balance and glutathione peroxidase (GSH-Px) activity regardless of dietary selenium levels. Therefore, there might be a considerable interaction between guar gum and selenium bioutilization in humans.
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