Increased Concentrations of Serotonin and 5-Hydroxyindoleacetic Acid in Blood Plasma from Patients with Pulmonary Hypertension due to Mitral Valve Disease
2009
Kirillova, V. V | Nigmatullina, R. R | Dzhordzhikiya, R. K | Kudrin, V. S | Klodt, P. M
Serotonin content in the plasma and platelets and 5-hydroxyindoleacetic acid concentration in the plasma were shown to increase in patients with pulmonary arterial hypertension due to mitral valve disease. A positive correlation was found between the severity of pulmonary arterial hypertension and concentrations of serotonin (r=0.48) and 5- hydroxyindoleacetic acid in the plasma (r=0.9).
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