Homotropic and heterotropic interactions in cytochromes c₃ from sulphate reducing bacteria
2012
Turner, David L. | Catarino, Teresa
This article reviews the contribution of António Xavier and his associates to the study of multihaem cytochromes. Detailed analysis of interactions between the charges of the haems and protonatable groups reveals that electrostatic effects may be outweighed by subtle changes in conformation. This helps us to understand how tetrahaem cytochromes c₃ work and also gives an insight into the mechanism of cytochrome c oxidase.
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