Effect of alternate high carbohydrate and high fat diets on insulin function
1980
Maji, Taizo | Yoshida, Akira | Ashida, Kiyoshi
Serum insulin and glucose were measured 2 hours after glucose was administered to rats who had been continuously fed a high carbohydrate (HCD) or high fat (HFD) diet, or both diets alternately for 2-day periods. Some groups were subsequently force fed corn oil. Serum glucose correlated with serum insulin in animals not fed corn oil. Alternate diets followed by corn oil feeding resulted in lower serum glucose and higher liver glycogen, but similar insulin levels, than did HCD followed by corn oil. Rats on HCD followed by corn oil also exhibited lower glucose tolerance after injection with insulin than did animals fed alternate diets and corn oil. Alternate diets appear to prevent decrease of insulin secretion in response to glucose after fat ingestion, and increase glycogen content of the liver after corn oil feeding. Alternate diets may prevent impairment of glucose tolerance by increasing insulin sensitivity and accumulation of liver glycogen. Thus, a change in feeding schedule affects insulin function to enhance glucose tolerance.
Show more [+] Less [-]AGROVOC Keywords
Bibliographic information
This bibliographic record has been provided by National Agricultural Library