Chemical composition, antiradical, and enzyme inhibitory potential of essential oil obtained from aerial part of Centaurea pterocaula Trautv
2021
Sen, Ali | Kurkcuoglu, Mine | Yildirim, Aybeniz | Senkardes, Ismail | Bitis, Leyla | Başer, K. H. C. (Kemal Hüsnü Can)
The chemical composition, free radical scavenging, α-amylase inhibitory, and 5-lipoxygenase inhibitory activity of the essential oil obtained from the aerial parts of Centaurea pterocaula Trautv. were examined. Twenty-nine compounds corresponding to 93.2% of the oil were identified in the oil of C. pterocaula. Hexadecanoic acid (13.9%), caryophyllene oxide (11.5%), spathulenol (11.4%), (E)-β-damascenone (5.0%), hexahydrofarnesyl acetone (5.0%), and tetradecanoic acid (4.9%) were the main compounds of the oil. The oil exhibited good anti‐inflammatory activity, inhibiting 5-lipoxygenase with an IC₅₀ value of 86.22 µg/mL. The oil was found to be active against DPPH radical and α-amylase with IC₅₀ values of 83.05 and 79.66 µg/mL respectively, while it showed moderate activity against ABTS radicals with IC₅₀ value of 360.9 µg/mL. To the best of our knowledge, this is first report on the chemical composition of C. pterocaula essential oil from Turkey; as well as on the biological activity of its essential oil.
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