Variable Selection in HighâDimensional Multivariate Binary Data with Application to the Analysis of Microbial Community DNA Fingerprints
2002
Wilbur, J. D. | Ghosh, J. K. | Nakatsu, C. H. | Brouder, S. M. | Doerge, R. W.
In order to understand the relevance of microbial communities on crop productivity, the identification and characterization of the rhieosphere soil microbial community is necessary. Characteristic profiles of the microbial communities are obtained by denaturing gradient gel electrophoresis (DGGE) of polymerase chain reaction (PCR) amplified 16s rDNA from soil extracted DNA. These characteristic profiles, commonly called community DNA fingerprints, can be represented in the form of highâdimensional binary vectors. We address the problem of modeling and variable selection in highâdimensional multivariate binary data and present an application of our methodology in the context of a controlled agricultural experiment.
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