Chemical properties and antiulcerogenic activity of a galactomannoglucan from Syagrus oleracea
2010
da Silva, Bernadete Pereira | Parente, José Paz
A galactomannoglucan (GMG) with an estimated weight-average molar mass of 415,000g/mol was obtained from an aqueous extract of the mesocarp of fruits of Syagrus oleracea (Mart.) Becc. by fractionation by Sephacryl S-300 HR and Sephadex G-25. Chemical and spectroscopic studies indicated that GMG has a chain of (1→4)-linked β-d-mannopyranosyl residues attached to an initial chain of (1→3)-linked β-d-galactopyranosyl residues and a terminal chain of (1→4)-linked α-d-glucopyranosyl residues which comprised galactose, mannose and glucose in the molar ratio of 30:33:37. Results of the present study indicated that the polysaccharide GMG of S. oleracea significantly inhibited gastric lesions induced by ethanol, showing a gastroprotective property.
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