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Pharmacokinetics of butorphanol tartrate in rabbits

1992

Portnoy, L.G. | Hustead, D.R.

The pharmacokinetic properties of butorphanol tartrate were determined in 7 rabbits after iv and sc injection (0.5 mg/kg of body weight). A 2-compartment model (biexponential) best represented the concentration vs time curve after IV injection. The half-life was calculated to be 1.64 hours via IV administration, whereas SC injection resulted in an elimination half-life of 3.16 hours.

AGROVOC Keywords

analgesics animals intravenous injection metabolism pharmacokinetics rabbits rabbits subcutaneous injection tissue distribution

Bibliographic information

Published in

American journal of veterinary research

ISSN 0002-9645

Publisher

Elsevier B.V.

Other Subjects

Half-life; Female; Veterinary; Half life; Injections; Subcutaneous; Male; Injections; Intravenous; Administration & dosage; Butorphanol

Language

English

Type

Journal Article; Text

In AGRIS since: 2024-02-29

Format: MODS

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