Highly selective two-photon imaging of cysteine in cancerous cells and tissues
2015
Lee, Yun Hak | Ren, Wen Xiu | Han, Jiyou | Sunwoo, Kyoung | Lim, Ja-Yun | Kim, Jong-Hoon | Kim, Jong Seung
Abnormal concentrations of Cys have been reported to be implicated in various health problems, including cancer, neuropathy, and cardiomyopathy. We present a novel two-photon fluorescent probe for the specific recognition of cysteine over homocysteine and glutathione, and the bioapplication of this probe for the imaging of live cancerous cells and thick tissues.
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