Biochemical observations during total starvation in dogs
1979
Bruijne, Jan J. de
Eighteen dogs (12 obese and six of normal body weight) were subjected to total starvation for three weeks. The biochemical effects were observed and compared. For the 12 obese dogs, no clinical or chemical changes occurred that would necessitate discontinuation of starvation; 16 parameters were measured. For these dogs, average weight loss was 18 percent; no significant changes were found in hematocrit, glucose, or in potassium or acid-base state; plasma levels of urea, sodium and calcium decreased slightly. For the six normal dogs, apart from minor changes, slightly decreased glucose levels were found; the following net losses were calculated--sodium 3.2 percent, potassium 16 percent, calcium 0 percent, and magnesium 6 percent. The treatment of obesity in dogs by total starvation is both safe and effective.
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