Fluorescent imaging of cytoplasmic nucleolin in live cells by a functionalized-engineered aptamer
2020
Yin, Junfa | Chen, Shaokun | Song, Yuanyuan | Wang, Hailin
Monitoring of over-expressed nucleolin in the cytoplasm facilitates early cancer diagnosis. Herein, we present a novel biosensing nanoscaffold based on anti-nucleolin aptamers and polymer-grafted graphene oxides for the fluorescent imaging of nucleolin in the cell cytoplasm, which can distinguish cancer cells from normal cells.
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