Synchronized navigation and comparative analyses across Ensembl complete bacterial genomes with INSYGHT.
2016
Lacroix, Thomas | Thérond, Sylvie | Rugeri, Marc | Nicolas, Pierre, P. | Gendrault, Annie | Loux, Valentin | Gibrat, Jean-François | Mathématiques et Informatique Appliquées du Génome à l'Environnement [Jouy-En-Josas] (MaIAGE) ; Institut National de la Recherche Agronomique (INRA) | Institut du développement et des ressources en informatique scientifique (IDRIS) ; Centre National de la Recherche Scientifique (CNRS)
International audience
Show more [+] Less [-]English. Motivation: High-throughput sequencing technologies provide access to an increasing number of bacterial genomes. Today, many analyses involve the comparison of biological properties among many strains of a given species, or among species of a particular genus. Tools that can help the microbiologist with these tasks become increasingly important. Results: Insyght is a comparative visualization tool whose core features combine a synchronized navigation across genomic data of multiple organisms with a versatile interoperability between complementary views. In this work, we have greatly increased the scope of the Insyght public data- set by including 2688 complete bacterial genomes available in Ensembl thus vastly improving its phylogenetic coverage. We also report the development of a virtual machine that allows users to easily set up and customize their own local Insyght server.
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