Comparative Analysis of the Expression of MHC-I, CD90, and CD29 in Equine Adipose-Derived and Marrow-Derived Mesenchymal Stem Cells
2021
Nazari, Fatemeh | Parham, Abbas | Fani Maleki, Adham
BACKGROUND: Several studies have reported the application of mesenchymal stem cells (MSCs) for the treatment of equine musculoskeletal disorders. Bone marrow (BM) and adipose tissue (AT) are the main sources for isolation of MSCs. Although the MSCs derived from various sources have similarities, certain differences have been reported in terms of biological, proliferative, immunological, and differentiative characteristics. They are also different concerning gene expression profiles. So, comparative gene expression analysis on mRNA level via quantitative real-time polymerase chain reaction (qRT-PCR) is believed to be of great value for better characterization of MSCs from different sources.
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