The pig: a model for human infectious diseases
2012
Meurens, Francois | Summerfield, Artur | Nauwynck, Hans | Saif, Linda | Gerdts, Volker | Infectiologie et Santé Publique (UMR ISP) ; Institut National de la Recherche Agronomique (INRA)-Université de Tours (UT) | Office Vétérinaire Fédéral (OVF) | Universiteit Gent = Ghent University = Université de Gand (UGENT) | Ohio University | University of Saskatchewan [Saskatoon, Canada] (U of S)
International audience
Show more [+] Less [-]English. An animal model to study human infectious diseases should accurately reproduce the various aspects of disease. Domestic pigs (Sus scrofa domesticus) are closely related to humans in terms of anatomy, genetics and physiology, and represent an excellent animal model to study various microbial infectious diseases. Indeed, experiments in pigs are much more likely to be predictive of therapeutic treatments in humans than experiments in rodents. In this review, we highlight the numerous advantages of the pig model for infectious disease research and vaccine development and document a few examples of human microbial infectious diseases for which the use of pigs as animal models has contributed to the acquisition of new knowledge to improve both animal and human health.
Show more [+] Less [-]Bibliographic information
This bibliographic record has been provided by Institut national de la recherche agronomique