Congenital Cerebellar Cortical Degeneration in Holstein Cattle in Southern Brazil
2001
Schild, Ana Lucia | Riet-Correa, Franklin | Portiansky, Enrique Leo | Méndez, M. C. | Graça, D. L.
A congenital progressive cerebellar disorder is described in Holstein calves. The clinical signs were progressive and were characterized by ataxia, hypermetria, a wide stance and fine head tremors. When the affected cattle were forced to run, the signs were exacerbated, leading to epileptiform attacks. Histological lesions consisted of a very selective cerebellar cortical degeneration, almost exclusively affecting the Purkinje cells. The disease affected 6 out of 200 Holstein calves from the same bull. However, results of mating tests of the bull with his daughters and granddaughters suggested that it was not hereditary (p = 0.0062) although an environmental–genetic interaction could not be ruled out.
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