Control genético del quimiotipo en Cannabis sativa | Genetic control of the chemotype in Cannabis sativa
2023
Gila Navarro, Alberto | Weiss, Julia Rosl | Egea Gutiérrez-Cortines, Marcos
[SPA] El modelo actual de herencia del quimiotipo en Cannabis sativa se centra en las dos sintasas terminales de la ruta biosintética de los cannabinoides, THCAS y CBDAS. Sin embargo, el modelo ignora la posible contribución de la regulación de la expresión génica de estas enzimas a la determinación del quimiotipo. En el presente trabajo en curso se muestra una red de regulación génica con los posibles factores de transcripción que regulan a THCAS y CBDAS y se debaten posibles implicaciones. [ENG] The current model of chemotype inheritance in Cannabis sativa revolves around the two terminal synthases of the cannabinoid biosynthesis pathway, the THCAS and CBDAS. However, the model ignores the possible contribution of the regulation of these enzymes’ gene expression to the determination of the chemotype. In the present on-going work, we present a gene regulatory network inferred in silico with the candidate transcription factors that regulate the expression of the THCAS and CBDAS and discuss possible implications.
Show more [+] Less [-]This work was funded by Project PID2021-127933OB-C21 financed by MCIN/AEI/10.13039/501100011033 and FEDER to M. Egea-Cortines and J. Weiss. A. Gila- Navarro received an FPU fellowship FPU21/02130 from the Spanish Ministry of Universities
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