Evaluation of a diagnostic model for aflatoxicosis in sheep: A prerequisite for future adoption of national surveillances
2014
Barbour E.K. | Abou-Alsaud M.E. | Gheith N.A. | Abdel-Sadek M.A. | Heba H.M.A. | Harakeh S. | Karrouf G.I.A. | Barbour, E.K., Department of Animal and Veterinary Sciences, American University of Beirut, P.O. Box 11-0236, Beirut, Lebanon, Biochemistry Department, King Abdulaziz University (KAU), Jeddah, Saudi Arabia | Abou-Alsaud, M.E., Biological Science Department, King Abdulaziz University, Jeddah 21589, Saudi Arabia | Gheith, N.A., Public Administration Departments, King Abdulaziz University, Saudi Arabia | Abdel-Sadek, M.A., Biological Science Department, King Abdulaziz University, Jeddah 21589, Saudi Arabia, Vacsera, Agouza, Giza, Egypt | Heba, H.M.A., Biological Science Department, King Abdulaziz University, Jeddah 21589, Saudi Arabia | Harakeh, S., Special Infectious Agents Unit - Biosafety Level 3, King Fahd Medical Research Center, King Abdulaziz University, Jeddah 21589, Saudi Arabia | Karrouf, G.I.A., King Fahd Medical Research Center King, Abdulaziz University, P.O. Box 80216, Jeddah 21589, Saudi Arabia, Anaesthesiology and Radiology Department, Mansoura University, 35516 Mansoura, Egypt | Barbour, E. K.; Department of Animal and Veterinary Sciences, American University of Beirut, P.O. Box 11-0236, Beirut, Lebanon; email: [email protected] | University: American University of Beirut; Faculty: Faculty of Agricultural and Food Sciences; Department: Animal and Veterinary Sciences; | Animal and Veterinary Sciences | [email protected] | Faculty of Agricultural and Food Sciences | Barbour, EK | Abou-Alsaud, ME | Gheith, NA | Abdel-Sadek, MA | Heba, HMA | Harakeh, S | Karrouf, GIA | Karrouf, Gamal-0000-0002-2260-5620 | Barbour, EK (reprint author), Amer Univ Beirut, Dept Anim and Vet Sci, Fac Agr and Food Sci, POB 11-0236, Beirut, Lebanon. | Karrouf, Gamal-D-5810-2013 | American University of Beirut
The aim of this research is to evaluate a diagnostic model for uncovering an aflatoxicosis outbreak in sheep. The diagnostic model is based on differentiation between an aflatoxicosis suspected herd (ASH) and a control herd (CH) including, clinical findings, feed analysis for aflatoxin and othernutrients, hemato-chemical and biochemical profiles, histopathologic changes, and residual aflatoxin levels in their organs. There was a significant difference between the sheep of the ASH and CH in relation to mortality percent, symptoms, aflatoxin B1 level in their feed and tissues, hematological and biochemical parameters, liver and kidney enzymes and metabolites, serum electrolytes, and vitamins A and E. The relationship of the histopathological lesions of affectedtissues to the aflatoxin B1 is discussed. This diagnostic model resulted in significant differences among many assigned parameters in ASH compared to the CH, allowing for its future adoption in national surveillances of aflatoxicosis in sheep.
Show more [+] Less [-]Alexander J., 2004, EFSA J, V34, P1; Alpsoy L, 2011, VITAM HORM, V86, P287, DOI 10.1016-B978-0-12-386960-9.00012-5; Alwakeel Suaad S, 2009, Pak J Biol Sci, V12, P637, DOI 10.3923-pjbs.2009.637.642; [Anonymous], 2007, 15550 DIN EN; [Anonymous], 2011, SPECULUM, V86, P1; AOAC, 1995, OFF METH AN; Bancroft JD, 1996, THEORIES PRACTICE HI; Cork SC, 2002, VETERINARY LAB FIELD; Dersjant-Li YM, 2003, NUTR RES REV, V16, P223, DOI 10.1079-NRR200368; Devegowda G., 2005, The mycotoxin blue book, P25; Drupt F, 1974, PHARM BIO, V9, P777; Feldman F, 2000, SCHALMS VETERINARY H; Gagini TB, 2010, BRAZ J MICROBIOL, V41, P345, DOI 10.1590-S1517-838220100002000013; HENDRICKSE R G, 1991, Annals Academy of Medicine Singapore, V20, P84; Iowa State University, 2009, AFL CORN; ITO Y, 1989, MUTAT RES, V222, P253, DOI 10.1016-0165-1218(89)90141-9; Kaaya AN, 2006, J APPL SCI, V52, P2401; KIND PRN, 1954, J CLIN PATHOL, V7, P322, DOI 10.1136-jcp.7.4.322; Mohamed A. M., 2009, Journal of Pharmacology and Toxicology, V4, P1, DOI 10.3923-jpt.2009.1.16; Orsi RB, 2007, CHEM-BIOL INTERACT, V170, P201, DOI 10.1016-j.cbi.2007.08.002; Ossati P., 1980, CLIN CHEM, V26, P227; Vinayak Patel, 2006, Pakistan Journal of Biological Sciences, V9, P1104; Peraica M, 1999, B WORLD HEALTH ORGAN, V77, P754; PETERS T, 1968, CLIN CHEM, V14, P1147; Probakaran JJ, 2009, ASIAN J BIOTECHNOL, V1, P104; RAISUDDIN S, 1993, MYCOPATHOLOGIA, V124, P189, DOI 10.1007-BF01103737; REITMAN S, 1957, AM J CLIN PATHOL, V28, P56; Riley RT, 1996, HUMAN ANIMAL RELATIO, P193; Saini SS, 2012, GLOBAL ADV RES J CHE, V1, P63; SEELIG H P, 1969, Aerztliche Laboratorium, V15, P34; Thoolen B, 2010, TOXICOL PATHOL, V38, p5S, DOI 10.1177-0192623310386499; TUNG HT, 1975, POULTRY SCI, V54, P1962; Yiannikouris A., 2002, INRA Productions Animales, V15, P3; Yousef MI, 2003, J ENVIRON SCI HEAL B, V38, P193, DOI 10.1081-PFC-120018449
Show more [+] Less [-]AGROVOC Keywords
Bibliographic information
This bibliographic record has been provided by American University of Beirut