Epigenetic landscape of pancreatic neuroendocrine tumours reveals distinct cells of origin and means of tumour progression
2020
Annunziata Di Domenico | Christodoulos P. Pipinikas | Renaud S. Maire | Konstantin Bräutigam | Cedric Simillion | Matthias S. Dettmer | Erik Vassella | Chrissie Thirlwell | Aurel Perren | Ilaria Marinoni
Di Domenico et al., provide a comprehensive assessment of DNA methylation in a large cohort of pancreatic neuroendocrine tumors. This work provides new insights into the epigenetic heterogeneity of the disease and cellular basis.
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