Quality Control, Phytochemical Profile, and Antibacterial Effect of <i>Origanum compactum</i> Benth. Essential Oil from Morocco
2022
Mouhcine Hayani | Noureddine Bencheikh | Atika Ailli | Mohamed Bouhrim | Amine Elbouzidi | Hayat Ouassou | Loubna Kharchoufa | Abdellah Baraich | Aziza Atbir | Fatima Zahra Ayyad | Aziz Drioiche | Mohamed Addi | Christophe Hano | Touriya Zair
<i>Origanum compactum</i> Benth (<i>O. compactum</i>) is widely used traditionally in Morocco to treat a broad range of illnesses, including infectious diseases. The aim of this study was to evaluate the phytochemical composition, quality control, and antibacterial activity of <i>O. compactum</i> leaf and flower essential oil. First, a quality control study on soil and irrigation water was performed to determine whether there was any risk of heavy metals endangering human health or causing stress to the plants studied. Laboratory examination of the environmental quality of the researched species revealed an almost absolute absence of metals that could endanger human health or any abiotic stressor. The essential oil was extracted by hydrodistillation. Chemical characterization was performed using gas chromatography-mass spectrometry (GC/MS). The yield of essential oil (EO) obtained by hydrodistillation of <i>O. compactum</i> leaves and flowers and moisture content were 4.27% and 12.20%, respectively. GC/MS identified 35 volatile compounds in the studied EO majorly composed of thymol (38.59%) followed by carvacrol (26.65%), o-cymene (14.33), and γ-terpinene (11.22%). The antibacterial activity of <i>O. compactum</i> leaf and flower essential oil was evaluated using the solid-state diffusion method against five Gram-negative bacterial strains and a Gram-positive strain. The results show that the essential oil of <i>O. compactum</i> leaves and flowers has a considerable inhibitory effect against <i>E. coli</i> with an MIC = 0.35 µg/mL, <i>E. pseudocoloides</i> (MIC = 0.35 µg/mL), <i>E. vekanda</i> (MIC = 0.35 µg/mL), <i>K. pneumoniae</i> (MIC = 0.7 µg/mL), <i>P. aeruginosa</i> (MIC = 0.35 µg/mL), and <i>S. aureus</i> (MIC = 0.35 µg/mL).
Show more [+] Less [-]AGROVOC Keywords
Bibliographic information
This bibliographic record has been provided by Directory of Open Access Journals