Protective efficacy of a formalin-inactivated vaccine against viral hemorrhagic septicemia (VHS) in oblong rockfish Sebastes oblongus
2019
Isshiki, T. (Mie University, Tsu, Mie (Japan). Graduate School of Bioresources) | Nagano, T.
We evaluated the protection against viral challenge afforded to oblong rockfish Sebastes oblongus by vaccination with formalin-inactivated VHS virus. The cumulative mortalities in the fish that received the vaccine at 12℃ and 20℃ were significantly lower than those in the control fish given PBS at the same temperatures (P<0.01). The relative percentage survival of all the vaccinated fish was 100%. Therefore, immunization with the formalin-inactivated vaccine at both 20℃ and 12℃ provided significant protection to oblong rockfish against VHS. This is the first report of an efficient vaccine against VHS in the oblong rockfish.
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