US EPA: Is there room to open a new window for evaluating potential sub-threshold effects and ecological risks?
2021
Agathokleous, Evgenios | Barceló, Damià | Calabrese, Edward J. | Barceló, Damià [0000-0002-8873-0491] | Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]
With a rule published on 6 January 2021, the US Environmental Protection Agency (EPA) considers for the first time sub-threshold responses, abandoning the use of default dose-response models. This may affect worldwide scientific research, in terms of research design and methodology, and regulatory actions in China and other countries.
Show more [+] Less [-]This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors. E.A. acknowledges multi-year support from The Startup Foundation for Introducing Talent of Nanjing University of Information Science and Technology, Nanjing, China (No. 003080 to E.A.). E.J.C. acknowledges longtime support from the U.S. Air Force (AFOSR FA9550-13-1-0047) and ExxonMobil Foundation (S18200000000256). The sponsors were not involved in the study design; the collection, analysis or interpretation of the data; the preparation of the manuscript or the decision where to submit the manuscript for publication.
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