Emergence of bluetongue virus serotype 6 in Europe-German field data and experimental infection of cattle
2010
Moss, A. | Savini, G. | Leone, A. | Zemke, Johanna Marie Luise | Eschbaumer, Michael | Hoffmann, Bernd | König, Patricia | Conraths, Franz Josef | Beer, Martin
In late 2008, bluetongue virus (BTV) serotype 6 (BTV-6), which had never occurred in Europe before, was first detected in the Netherlands and Germany. While the origin of the virus remains unknown, the prevalence of infections in cattle was investigated in a virological (N=28,658) and serological (N=2075) field survey in Lower Saxony, where 45 cases confined to the district Grafschaft Bentheim were found. Blood from affected animals was used for the experimental infection of three cattle with different BTV antibody status, leading to sustained viraemia in one animal naive for BTV. Of two animals that had detectable antibodies against BTV serotype 8, one became transiently infected and seroconverted for BTV-6 while the other did not react. In conclusion, while only a very limited spread of BTV-6 could be observed in the field, experimental infection of cattle did not show substantial differences of the course of infection in comparison to other BTV serotypes. (C) 2009 Elsevier B.V. All rights reserved
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Publisher Elsevier Science
ISSN 1873-2542 | 0378-1135This bibliographic record has been provided by Friedrich-Loeffler-Institut
