Preliminary genome-wide association study for skin traits in an Angora x creole backcross population

Angora goat produce mainly mohair fiber but the Creole goats have a double hair coat: cashmere, fine and short seasonal down coat and coarser and longer guard hair. Both, mohair and cashmere fiber are determined by two types of skin hair follicle, primary and secondary and several phenotypes can be drawn from them like S/P ratio. The aim of this study was to identify polymorphisms associated with skin traits in a backcross Angora x Creole goats (n=477) using a SNP-based GWAS analysis. Significant regions on CHIR 1, 2, 6, and X exhibit a maximum signal for seven SNP markers with a p-value from 8.16E-06 to 1.26E-04. These results indicate that may be several genes that could be involved in skin traits close to the most significant SNP markers in this backross Angora x Creole population.

Instituto de Genética

Fil: Cano Pereira, Ema Margarita. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Genética; Argentina

Fil: Debenedetti, Sebastián. Ministerio de Agricultura, Ganadería y Pesca de la Nación; Argentina

Fil: Giovannini, Nicolas. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Bariloche

Fil: Taddeo, Héctor Raúl. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Bariloche; Argentina

Fil: Poli, Mario Andres. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Genética; Argentina