Pour on dehelmintizacija domaćih brdskih konja

Preliminary research of the domestic hilly horse parasitofauna determined the invasion with different types of endoparasites. Detailed examination included six domestic hilly horses, where the following parasites were found: Strongylus edentatus, Dictyocaulus arnfieldi and Parascaris equorum. The intensity of the infection was medium the highest in strongiloidosis and parascariosis, so that the number of eggs of Trychostrongylus axei and Dictyocaulus arnfiledi was ten times lower. All horses in the experiment were clinically healthy, with no visible symptoms of the disease, regardless of the type of parasites identified and the intensity of the infection. In the observed period of 10 weeks, before and after the application of anthelmintics, no visible changes in behavior were found, as well as no signs of the disease. Ivermectin was effective against all these parasites, with the fastest effect, jud ged by the dynamics of parasite eggs elimination, observed in the control of stongilides. Elimination of Strongylus edentatus eggs was the shortest, only 4 days. Similar effects were seen in Dictyocaulus arnfieldi infection, where egg elimination ceased 96 hours after treatment. Pour on application of ivermectin led to a somewhat slower elimination of Pa rascaris equorum eggs and also Trichostrongylus axei, which lasted for 10 days. The same parasites were individually identified on day 70 by coprologic exami nation in two horses. The highest concentration of the active substance in the blood of ivermectintreated horses was 2.93 ± 0.13 ng/ml, which was determi ned 48 hours following treatment. Almost identical ivermectin concentrations were maintained up to 96 hours after administration. The concentration of ivermectin in the serum of pour on treated horses was maintained until day 30, when the minimal concentration of 0.14 ± 0.04 ng / ml was determined. The efficacy of ivermectin has been demonstrated in all treated horses, but gi ven the mode of application and less exposure of animals to stress, the pour on application of ivermectin fully justified the goal we set in our study.